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<!DOCTYPE html>
<html lang="en">
<head>
<meta charset="UTF-8" />
<meta name="viewport" content="width=device-width, initial-scale=1.0"/>
<title>ℳöbius Framework — Medical Multimodal Mutual Supervision</title>
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</head>
<body>
<header>
<h1>ℳöbius Framework</h1>
<p class="subtitle">Closed-Loop Mutual Supervision for Reliable Medical Vision–Language Reasoning</p>
<div class="header-icons">
<a href="https://github.com/NJU-MedAI-Lab/mobius" target="_blank" rel="noopener" aria-label="GitHub">
<img src="./icons/github.svg" alt="GitHub" />
</a>
<a href="https://huggingface.co/NJU-MedAI-Lab" target="_blank" rel="noopener" aria-label="Hugging Face">
<img src="./icons/huggingface-color.svg" alt="Hugging Face" />
</a>
</div>
</header>
<main>
<section>
<h2>Overview</h2>
<p>
The <span class="highlight">Möbius Framework</span> addresses <strong>hallucination</strong> and <strong>modality laziness</strong> in medical large vision-language models (LVLMs) by establishing a bidirectional, closed-loop supervision between an LVLM and a Segment Anything Model (SAM).
</p>
<p>
Language from the LVLM guides anatomical segmentation, while segmentation from SAM grounds visual reasoning—enabling annotation-efficient alignment of perception and semantics.
</p>
</section>
<section>
<h2>Core Components</h2>
<div class="models">
<div class="model-card">
<div class="model-name">ℳöbiusMed-LVLM</div>
<p>A medical LVLM trained within the Möbius framework, producing visually grounded diagnostic descriptions with reduced hallucination.</p>
</div>
<div class="model-card">
<div class="model-name">ℳöbiusMed-SAM</div>
<p>A vision foundation model enhanced by linguistic guidance from the LVLM, capable of interpreting free-form medical instructions.</p>
</div>
</div>
</section>
<section>
<h2>Key Innovation</h2>
<p>
Unlike conventional pipelines that treat vision and language modules independently, Möbius creates a <span class="highlight">self-correcting loop</span>:
</p>
<ul style="padding-left: 1.5rem; margin: 1rem 0;">
<li>LVLM → SAM: Natural language prompts refine region-of-interest segmentation.</li>
<li>SAM → LVLM: Precise masks constrain visual grounding, suppressing unfaithful generation.</li>
</ul>
<p>
This mutual supervision mimics the Möbius strip—seamlessly connecting two modalities into a unified, self-reinforcing system.
</p>
</section>
</main>
<footer>
<p>Proposed by Xiao Song and Haonan Qin, <a href="https://prlab-nju.com/">PR-Lab</a> @ Nanjing University • 2025</p>
<p>For research purposes only. Part of doctoral work on medical multimodal reliability.</p>
</footer>
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