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transTarget

transTarget is an R package for visualizing genome-wide trans-acting genomic interactions using arc plots.

It is designed to map interactions from a single point (e.g. eRNA, enhancer, locus, mutation, gene) to multiple distal genomic targets across chromosomes using a concatenated genome representation.


πŸ“¦ Installation

  • devtools::install_github("nataliabenova/transTarget")

πŸš€ Quick Start

1. Load library

library(transTarget)

2. Load example dataset

data(eRNA_interactions)

3. Generate plot

arc_plot( eRNA_interactions, s = "support", l = "ID.y", n_bins = 2 )

Input Data Format

The input data frame must contain:

  • ID.x β€” anchor ID (must be a single unique value)
  • ID.y β€” target ID
  • chr.x, start.x, end.x β€” anchor coordinates
  • chr.y, start.y, end.y β€” target coordinates

Optional:

  • support β€” numeric evidence score (otherwise computed automatically)

Example Output

Arc plot example