FiO2Calculator.github.io/hybrid.html at main · FiO2Calculator/FiO2Calculator.github.io · GitHub

1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100
101
102
103
104
105
106
107
108
109
110
111
112
113
114
115
116
117
118
119
120
121
122
123
124
125
126
127
128
129
130
131
132
133
134
135
136
137
138
139
140
141
142
143
144
145
146
147
148
149
150
151
152
153
154
155
156
157
158
159
160
161
162
163
164
165
166
167
168
169
170
171
172
173
174
175
176
177
178
179
180
181
182
183
184
185
186
187
188
189
190
191
192
193
194
195
196
197
198
199
200
201
202
203
204
205
206
207
208
209
210
211
212
213
214
215
216
217
218
219
220
221
222
223
224
225
226
227
228
229
230
231
232
233
234
235
236
237
238
239
240
241
242
243
244
245
246
247
248
249
250
251
252
253
254
255
256
257
258
259
260
261
262
263
264
265
266
267
268
269
270
271
272
273
274
275
276
277
278
279
280
281
282
283
284
285
286
287
288
289
290
291
292
293
294
295
296
297
298
299
300
301
302
303
304
305
306
307
308
309
310
311
312
313
314
315
316
317
318
319
320
321
322
323
324
325
326
327
328
329
330
331
332
333
334
335
336
337
338
339
340
341
342
343
344
345
346
347
348
349
350
351
352
353
354
355
356
357
358
359
360
361
362
363
364
365
366
367
368
369
370
371
372
373
374
375
376
377
378
379
380
381
382
383
384
385
386
387
388
389
390
391
392
393
394
395
396
397
398
399
400
401
402
403
404
405
406
407
408
409
410
411
412
413
414
415
416
417
418
419
420
421
422
423
424
425
426
427
428
429
430
431
432
433
434
435
436
437
438
439
440
441
442
443
444
445
446
447
448
449
450
451
452
453
454
455
456
457
458
459
460
461
462
463
464
465
466
467
468
469
470
471
472
473
474
475
476
477
478
479
480
481
482
483
484
485
<!doctype html>
<html>

<head>
  <meta charset="utf-8">
  <meta name="viewport" content="width=device-width, initial-scale=1.0">
  <title>FiO2 Calculator</title>
  <link rel="stylesheet" href="style.css">
  <link rel="stylesheet" href="https://cdn.jsdelivr.net/npm/bootstrap@4.5.3/dist/css/bootstrap.min.css"
    integrity="sha384-TX8t27EcRE3e/ihU7zmQxVncDAy5uIKz4rEkgIXeMed4M0jlfIDPvg6uqKI2xXr2" crossorigin="anonymous">

  <script>
    changeCell = () => {
      let output = document.getElementById("output").value;
      switch (output) {
        case "fio2":
          return document.getElementById('last-cell').innerHTML = "Oxygen Flow (mL/min or cc/min)";

        case "flow":
          return document.getElementById('last-cell').innerHTML = "FiO2 (%)";

        default:
          return document.getElementById('last-cell').innerHTML = "Select Option Above"
      }
    };

    calculateFiner = () => {
      const weight = Number(document.getElementById('qty_weight').value);
      const respRate = Number(document.getElementById('qty_respiratory_rate').value);
      const B = Number(document.getElementById("qty_blender_oxygen").value); //%

      const Vt = 5.5 * weight;
      const Ve = Vt * respRate;

      let output = document.getElementById("output").value;
      let result = "Please select your desired output";
      let finerResult = 0;
      let finerWarning = "";
      let finerWarning2 = "";

      switch (output) {
        case "fio2":
          const flow = Number(document.getElementById('last-cell-value').value);

          let calculatedFio2 = 0;

          if (flow > 200) {
            //alert('Flow rate too high, please use a different calculator.');
            finerWarning = " Flow rate too high, results may be inaccurate.";
            //finerResult = "Out of range.";
          };

          if (flow > Ve) {
            calculatedFio2 = B;
            finerResult = Math.round(calculatedFio2);
          };

          if (flow <= Ve) {
            calculatedFio2 = (((flow * (B - 21) / 100) + (0.21 * Ve)) / Ve) * 100;
            finerResult = Math.round(calculatedFio2);
          };
          break;

        case "flow":
          const fio2 = Number(document.getElementById('last-cell-value').value);
          const maxFio2 = B;

          let calculatedFlow = 0;

          if (fio2 <= maxFio2) {
            calculatedFlow = (Ve / ((B - 21))) * ((fio2) - 21);
            finerResult = Math.round(calculatedFlow);
          };

          if (fio2 > maxFio2) {
            calculatedFlow = Ve;
            finerWarning2 = " The FiO2 value you entered cannot be reached with this blender oxygen. The max FiO2 possible is " + Math.round(maxFio2) + "% and the lowest flow rate at which it is reached is shown in the table below.";
            finerResult = Math.round(calculatedFlow);
          };

          if (calculatedFlow > 200) {
            //alert('Calculated flow rate too high, please use a different calculator.')
            finerWarning = " Calculated flow rate too high, results may be inaccurate.";
            //finerResult = "Out of range.";
          };

          break;

        default:
          finerResult = "Please select your desired output";
          break;
      }

      return [finerResult, finerWarning, finerWarning2]
    };

    calculateBB = () => {
      const weight = Number(document.getElementById('qty_weight').value); //kg
      const fNose = 0.67;
      const T = 0.3; //s
      const B = Number(document.getElementById("qty_blender_oxygen").value); //%

      const Vt = 5.0 * weight;
      const VdotNose = fNose * Vt / T;

      let output = document.getElementById("output").value;
      let result = "Please select your desired output";
      let bbWarning = "";
      let bbResult = 0;

      const maxFio2 = 21 + fNose * (B - 21);

      switch (output) {
        case "fio2":
          const flow = Number(document.getElementById('last-cell-value').value); //mL/min
          let factor = 0;

          const VdotNc = flow / 60; // mL/s

          if (VdotNose >= VdotNc) {
            factor = T * VdotNc / Vt;
          }
          if (VdotNose < VdotNc) {
            factor = fNose;
          }
          calculatedFio2 = 21 + factor * (B - 21);

          bbResult = Math.round(calculatedFio2);
          break;

        case "flow":
          const fio2 = Number(document.getElementById('last-cell-value').value);
          let calculatedFlow = 0;

          if (fio2 < maxFio2) {
            calculatedFlow = (Vt * (fio2 - 21)) / (T * (B - 21)) * 60;
          }

          if (fio2 >= maxFio2) {
            calculatedFlow = (Vt * (maxFio2 - 21)) / (T * (B - 21)) * 60;
            bbWarning = " The FiO2 value you entered cannot be reached with this blender oxygen. The max FiO2 possible is " + Math.round(maxFio2) + "% and the lowest flow rate at which it is reached is shown in the table below.";
          }

          bbResult = Math.round(calculatedFlow);

          break;

        default:
          bbResult = "Please select your desired output";
          break;
      }

      return [bbResult, bbWarning, maxFio2];
    };

    NICU = (W, R, F, B) => {
      let FiO2 = 0;

      const Ve = R * W * 5.5;

      if (F > Ve) {
        FiO2 = B;
      } else {
        FiO2 = ((F * (B - 21) / 100) + (0.21 * R * W * 5.5)) / (R * W * 0.055);
      };

      return FiO2
    };

    BB = (W, F, B) => {
      let FiO2 = 0;

      let factor = 0;
      const fNose = 0.67;
      const T = 0.3; //s

      const Vt = 5.0 * W;
      const VdotNose = fNose * Vt / T;
      const VdotNc = F / 60;

      if (VdotNose >= VdotNc) {
        factor = T * VdotNc / Vt;
      }
      if (VdotNose < VdotNc) {
        factor = fNose;
      }
      FiO2 = 21 + factor * (B - 21);
      return FiO2
    };

    hybrid = (flow) => {
      const W = Number(document.getElementById('qty_weight').value);
      const R = Number(document.getElementById('qty_respiratory_rate').value);
      const B = Number(document.getElementById("qty_blender_oxygen").value);

      const finer = NICU(W, R, flow, B);
      const bb = BB(W, flow, B);

      if (flow <= 200) {
        return [flow, (finer + bb) / 2];
      } else return [flow, bb];
    };

    makeArray = (steps) => {
      let arr = [0];
      for (let i = 0; i <= steps; i++) {
        arr.push(arr[i] + 1);
      };
      return arr;
    };

    getPolys = () => {
      //const regression = window.regression;
      const Fs = makeArray(2000);
      let hybridValues = [];

      for (i in Fs) {
        hybridValues.push(hybrid(i));
      };

      const coefficients = regression('polynomial', hybridValues, 2);

      return coefficients;
    }

    calculate = () => {
      document.getElementById('loading').innerHTML = "Calculating..";
      document.getElementById('warnings').innerHTML = "";

      const finer = calculateFiner();
      const bb = calculateBB();

      let polys = getPolys().equation;
      let d2 = polys[2];
      let d1 = polys[1];
      let d0 = polys[0];

      const outputValue = Number(document.getElementById('last-cell-value').value);

      let output = document.getElementById("output").value;
      let tableOutput = "";
      let hybrid = 0;
      let hybridWarning = "";

      let maxFlow = 0;

      if (d2 < 0) {
        maxFlow = Math.min((-d1 - Math.sqrt(d1 ** 2 - 4 * d2 * (d0 - bb[2]))) / (2 * d2), (-d1 + Math.sqrt(d1 ** 2 - 4 * d2 * (d0 - bb[2]))) / (2 * d2));
      } else {
        maxFlow = Math.max((-d1 - Math.sqrt(d1 ** 2 - 4 * d2 * (d0 - bb[2]))) / (2 * d2), (-d1 + Math.sqrt(d1 ** 2 - 4 * d2 * (d0 - bb[2]))) / (2 * d2));
      };

      switch (output) {
        case "fio2":
          if (outputValue < maxFlow) {
            hybrid = Math.round(d2 * (outputValue ** 2) + d1 * outputValue + d0);
          } else {
            hybrid = Math.round(bb[2]);
          };
          tableOutput = "FiO2 (%)";
          break;
        case "flow":
          let fio2 = outputValue;
          tableOutput = "Flow Rate (mL/min)";
          if (fio2 <= bb[2]) {
            let intercept = 0;
            if (d2 < 0) {
              intercept = Math.min((-d1 - Math.sqrt(d1 ** 2 - 4 * d2 * (d0 - fio2))) / (2 * d2), (-d1 + Math.sqrt(d1 ** 2 - 4 * d2 * (d0 - fio2))) / (2 * d2));
            } else {
              intercept = Math.max((-d1 - Math.sqrt(d1 ** 2 - 4 * d2 * (d0 - fio2))) / (2 * d2), (-d1 + Math.sqrt(d1 ** 2 - 4 * d2 * (d0 - fio2))) / (2 * d2));
            };
            hybrid = Math.round(intercept);
          } else {
            hybrid = Math.round(maxFlow);
            hybridWarning = " The FiO2 value you entered cannot be reached with this blender oxygen. The max FiO2 possible is " + Math.round(bb[2]) + "% and the lowest flow rate at which it is reached is shown in the table below.";
          }
          break;

        default:
          tableOutput = "Output";
          hybrid = "";
          break;
      };

      document.getElementById('loading').innerHTML = "<br />";
      document.getElementById('table-output').innerHTML = tableOutput;

      document.getElementById('table-finer').innerHTML = finer[0];
      document.getElementById('table-bb').innerHTML = bb[0];
      document.getElementById('table-hybrid').innerHTML = hybrid;

      const warnings = document.getElementById('warnings');
      const ul = document.createElement('ul');
      const liFiner1 = document.createElement('li');
      const liFiner2 = document.createElement('li');
      const liBB = document.createElement('li');
      const liHybrid = document.createElement('li');

      if (finer[1] != "") {
        liFiner1.innerHTML = ("<b>Finer:</b>" + finer[1]);
        ul.appendChild(liFiner1);
      } if (finer[2] != "") {
        liFiner2.innerHTML = ("<b>Finer:</b>" + finer[2]);
        ul.appendChild(liFiner2);
      } if (bb[1] != "") {
        liBB.innerHTML = ("<b>Benaron-Benitz:</b>" + bb[1]);
        ul.appendChild(liBB);
      } if (hybridWarning != "") {
        liHybrid.innerHTML = ("<b>Hybrid:</b>" + hybridWarning);
        ul.appendChild(liHybrid);
      };

      warnings.appendChild(ul);
      return
    };
  </script>

</head>

<body>
  <header>
    <h4>FiO2 Calculator</h4>
    <div class="nav">
      <ul>
        <li>
          <a href="aboutUs.html" class="btn btn-secondary" role="button" aria-pressed="true">
            About Us
          </a>
        </li>
      </ul>
    </div>
  </header>
  <nav class="navbar navbar-expand navbar-light bg-light">

    <div class="collapse navbar-collapse justify-content-center" id="navbarNav">
      <ul class="navbar-nav">
        <li class="nav-item active">
          <a class="nav-link" href="index.html">Home</a>
        </li>
        <li class="nav-item active">
          <div class="dropdown">
            <a class="nav-link active dropdown-toggle" type="button" id="dropdownMenuButton" data-toggle="dropdown"
              aria-haspopup="true" aria-expanded="false">
              Calculators
            </a>
            <div class="dropdown-menu" aria-labelledby="dropdownMenuButton">
              <a class="dropdown-item" href="finer.html">Finer</a>
              <a class="dropdown-item" href="bb.html">Benaron-Benitz</a>
              <a class="dropdown-item" href="hybrid.html">Hybrid</a>
            </div>
          </div>
        </li>
        <li class="nav-item active">
          <div class="dropdown">
            <a class="nav-link active dropdown-toggle" type="button" id="dropdownMenuButton" data-toggle="dropdown"
              aria-haspopup="true" aria-expanded="false">
              How it Works
            </a>
            <div class="dropdown-menu" aria-labelledby="dropdownMenuButton">
              <a class="dropdown-item" href="finerHIW.html">Finer</a>
              <a class="dropdown-item" href="bbHIW.html">Benaron-Benitz</a>
              <a class="dropdown-item" href="hybridHIW.html">Hybrid</a>
            </div>
          </div>
        </li>
      </ul>
    </div>
  </nav>

  <div class="page-content">
    <h5>Hybrid Calculator:</h5>
    <p>
      <b>Disclaimer:</b> This model has not been validated against real data (click <a href="hybridHIW.html">here</a>
      for more info).
    </p>
    <p> Recommended conditions for use:
    <ul>
      <li>If known, a flow rate below 2000 ml/min</li>
      <li>A measured respiratory rate</li>
    </ul>
    </p>

    <div class="container mt-4">
      <div class="row my-3">
        <div class="col-6">
          Weight (Kg)
        </div>
        <div class="col-3">
          <input type="number" value="1.5" class="qty" id="qty_weight" />
        </div>
      </div>

      <div class="row my-3">
        <div class="col-6">
          Blender Oxygen (%)
        </div>
        <div class="col-3">
          <input type="number" value="100" class="qty" id="qty_blender_oxygen" />
        </div>
      </div>

      <div class="row my-3">
        <div class="col-6">
          Respiratory rate (Breaths/Min)
        </div>
        <div class="col-3">
          <input type="number" value="65" class="qty" id="qty_respiratory_rate" />
        </div>
      </div>

      <div class="row my-3">
        <div class="col-6">
          Preferred output:
        </div>
        <div class="col-3" onload="changeCell()">
          <select id="output" onchange="changeCell()">
            <option value="none">Select Option</option>
            <option value="fio2">FiO2</option>
            <option value="flow">Flow Rate</option>
          </select>
        </div>
      </div>

      <div class="row my-3">
        <div class="col-6" id=last-cell>Select Option Above</div>
        <div class="col-3">
          <input type="number" class="qty" value="0" id="last-cell-value" />
        </div>
      </div>

    </div>

    <p class="result-div">
    <div class="center" onload="calculate()">
      <button class="btn btn-success" type="button" onclick="calculate()">Calculate Results</button>
    </div>
    <div class="loading" id="loading"><br /></div>

    <p class="warnings">Warnings:
    <ul id="warnings">(If a warning comes up it will appear here)</ul>
    </p>

    <table class="table">
      <tr>
        <th>Model</th>
        <th id="table-output">Output</th>
      </tr>
      <tr>
        <td>Finer (NICU)</td>
        <td id="table-finer"></td>
      </tr>
      <tr>
        <td>Benaron-Benitz</td>
        <td id="table-bb"></td>
      </tr>
      <tr style="outline: 1px solid black;">
        <td>Hybrid</td>
        <td id="table-hybrid"></td>
      </tr>
    </table>
    </p>
    <p xmlns:cc="http://creativecommons.org/ns#">This work is licensed under <a
        href="http://creativecommons.org/licenses/by-nc-sa/4.0/?ref=chooser-v1" target="_blank"
        rel="license noopener noreferrer" style="display:inline-block;">CC BY-NC-SA 4.0<img
          style="height:22px!important;margin-left:3px;vertical-align:text-bottom;"
          src="https://mirrors.creativecommons.org/presskit/icons/cc.svg?ref=chooser-v1"><img
          style="height:22px!important;margin-left:3px;vertical-align:text-bottom;"
          src="https://mirrors.creativecommons.org/presskit/icons/by.svg?ref=chooser-v1"><img
          style="height:22px!important;margin-left:3px;vertical-align:text-bottom;"
          src="https://mirrors.creativecommons.org/presskit/icons/nc.svg?ref=chooser-v1"><img
          style="height:22px!important;margin-left:3px;vertical-align:text-bottom;"
          src="https://mirrors.creativecommons.org/presskit/icons/sa.svg?ref=chooser-v1"></a></p>

  </div>

  <script src="https://code.jquery.com/jquery-3.5.1.slim.min.js"
    integrity="sha384-DfXdz2htPH0lsSSs5nCTpuj/zy4C+OGpamoFVy38MVBnE+IbbVYUew+OrCXaRkfj"
    crossorigin="anonymous"></script>
  <script src="https://cdn.jsdelivr.net/npm/bootstrap@4.5.3/dist/js/bootstrap.bundle.min.js"
    integrity="sha384-ho+j7jyWK8fNQe+A12Hb8AhRq26LrZ/JpcUGGOn+Y7RsweNrtN/tE3MoK7ZeZDyx"
    crossorigin="anonymous"></script>
  <script src="https://cdnjs.cloudflare.com/ajax/libs/regression/1.4.0/regression.min.js"></script>
</body>

</html>