diff --git a/changelog.d/10650-symbol-iterator-generator-this.md b/changelog.d/10650-symbol-iterator-generator-this.md
new file mode 100644
index 0000000000..360d715b5e
--- /dev/null
+++ b/changelog.d/10650-symbol-iterator-generator-this.md
@@ -0,0 +1,26 @@
+Fixed: a class generator method keyed by `[Symbol.iterator]`, when a `for…of`
+loop inside it iterated a method call on `this` (`for (const x of
+this.gen()) yield x;`), saw `this === undefined` and threw `Cannot read
+properties of undefined (reading 'gen')`. Every consumer that dispatches
+through the class's iterator protocol (`for…of`, spread, `Array.from`) hit it
+identically; the identical body under an ordinary method name worked.
+
+Root cause: lifting a `*[Symbol.iterator]()` method to its top-level
+generator (`synthesize_symbol_iterator_wrapper`) rewrites `this` to an
+explicit parameter via `replace_this_in_stmts`/`replace_this_in_expr`
+(`crates/perry-hir/src/analysis.rs`). That rewrite had no arm for
+`Expr::GetIterator`/`GetAsyncIterator`/`MapEntries`/`SetValues` — the wrapper
+expressions a `for…of` iterable lowers to when it can't be proven a plain
+Array/Map/Set — so a `this` buried inside one of those wrappers fell through
+to the catch-all and was never rewritten.
+
+Fix: added the four missing arms, recursing into the wrapped expression the
+same way the existing `Await`/`TypeOf`/`Void` arms do.
+
+Validation: new gap test (`test_gap_10445_symbol_iterator_generator_this.ts`)
+covering the issue repro plus a two-level generator chain, a
+`Symbol.iterator` generator on a class expression, and `yield*` delegation
+alongside a `for…of` over `this.method()` — proven to fail on the pre-fix
+tree and pass on this one, byte-identical to Node 26.5.1. `cargo test
+--release -p perry-hir --tests`: 748 passed. Lint: 76/77 gates (the one red
+is the pre-existing, repo-wide benchmark-freshness check).
diff --git a/crates/perry-hir/src/analysis.rs b/crates/perry-hir/src/analysis.rs
index b9fba65cee..0b62440897 100644
--- a/crates/perry-hir/src/analysis.rs
+++ b/crates/perry-hir/src/analysis.rs
@@ -1154,6 +1154,25 @@ fn replace_this_in_expr(expr: &mut Expr, this_id: LocalId) {
             replace_this_in_expr(else_expr, this_id);
         }
         Expr::Await(inner) => replace_this_in_expr(inner, this_id),
+        // #10445: a `for…of`/`for await…of` iterable that can't be proven a
+        // plain Array/Map/Set lowers to one of these wrapper exprs around the
+        // ORIGINAL receiver expression (see `stmt_loops.rs`'s
+        // `lower_stmt_for_of_inner` — `Expr::GetIterator`/`GetAsyncIterator`
+        // wrap the lazy-iterator-protocol receiver, `MapEntries`/`SetValues`
+        // wrap a Map/Set whose fast path is disabled). Missing them here left
+        // a `for (const x of this.gen())` inside a lifted
+        // `*[Symbol.iterator]()` generator (`synthesize_symbol_iterator_wrapper`
+        // below, which lifts the method to a top-level function and replaces
+        // `this` with an explicit param) with an unreplaced `Expr::This` deep
+        // inside the wrapper — it fell through to the catch-all and evaluated
+        // to `undefined` outside any method body, `Cannot read properties of
+        // undefined (reading 'gen')`. Hoisting the same call into a local
+        // first (`const it = this.gen(); for (const x of it)`) sidestepped
+        // the bug because the plain `Stmt::Let` init IS a matched `Expr::Call`.
+        Expr::GetIterator(inner) | Expr::GetAsyncIterator(inner) => {
+            replace_this_in_expr(inner, this_id)
+        }
+        Expr::MapEntries(inner) | Expr::SetValues(inner) => replace_this_in_expr(inner, this_id),
         Expr::Yield { value, .. } => {
             if let Some(v) = value {
                 replace_this_in_expr(v, this_id);
diff --git a/test-files/test_gap_10445_symbol_iterator_generator_this.ts b/test-files/test_gap_10445_symbol_iterator_generator_this.ts
new file mode 100644
index 0000000000..a90843efb7
--- /dev/null
+++ b/test-files/test_gap_10445_symbol_iterator_generator_this.ts
@@ -0,0 +1,89 @@
+// #10445: a generator method keyed by `[Symbol.iterator]`, whose `for…of`
+// iterable is a method call on `this` (`for (const x of this.gen()) …`),
+// saw `this === undefined` inside the callee. Root cause:
+// `synthesize_symbol_iterator_wrapper` (lower_decl/class_decl.rs) lifts the
+// method's body to a top-level generator taking `this` as an explicit
+// param, then `replace_this_in_stmts`/`replace_this_in_expr` (analysis.rs)
+// rewrites every `Expr::This` in that body to the param. A `for…of` whose
+// iterable can't be proven a plain Array/Map/Set lowers to one of
+// `GetIterator`/`GetAsyncIterator`/`MapEntries`/`SetValues` wrapping the
+// receiver expression (stmt_loops.rs's `lower_stmt_for_of_inner`) -- and
+// `replace_this_in_expr` had no arm for any of those wrappers, so a `this`
+// buried inside one fell through to the catch-all and was left unreplaced.
+// Every consumer that dispatches through the lifted function (spread,
+// `for…of`, `Array.from`) hit the same bug identically.
+
+class Bag {
+  items = [1, 2];
+  *gen() {
+    yield* this.items;
+  }
+  *[Symbol.iterator]() {
+    for (const x of this.gen()) yield x; // the repro shape
+  }
+  *viaLocal() {
+    for (const x of this.gen()) yield x; // same body, ordinary name: control
+  }
+}
+
+// Two-level: the iterator method's for-of iterable is ANOTHER method whose
+// OWN for-of iterable is a THIRD method -- this must survive two hops of
+// the lifted-generator's this-substitution, not just one.
+class TwoLevel {
+  items = [10, 20, 30];
+  *inner() {
+    for (const x of this.items) yield x * 2;
+  }
+  *middle() {
+    for (const x of this.inner()) yield x + 1;
+  }
+  *[Symbol.iterator]() {
+    for (const x of this.middle()) yield x;
+  }
+}
+
+// Class EXPRESSION (not a declaration) -- the lift/this-rewrite must not be
+// keyed off a named-declaration-only path.
+const ExprClass = class {
+  items = ["a", "b", "c"];
+  *gen() {
+    yield* this.items;
+  }
+  *[Symbol.iterator]() {
+    for (const x of this.gen()) yield x;
+  }
+};
+
+// `yield*` delegation alongside a for-of over `this.method()` in the SAME
+// generator -- confirms the fix doesn't disturb the already-working
+// yield*-over-this.gen() path while also fixing the for-of one.
+class Mixed {
+  items = [1, 2, 3];
+  *gen() {
+    yield* this.items;
+  }
+  *[Symbol.iterator]() {
+    yield* this.gen();
+    for (const x of this.gen()) yield x * 10;
+  }
+}
+
+const show = (label: string, f: () => unknown) => {
+  try {
+    console.log(label, JSON.stringify(f()));
+  } catch (e: any) {
+    console.log(label, "threw:", e.message);
+  }
+};
+
+show("spread over *[Symbol.iterator]:", () => [...new Bag()]);
+show("for-of over *[Symbol.iterator]:", () => {
+  const out: number[] = [];
+  for (const x of new Bag()) out.push(x);
+  return out;
+});
+show("Array.from(bag):", () => Array.from(new Bag()));
+show("named generator, same body:", () => [...new Bag().viaLocal()]);
+show("two-level generator:", () => [...new TwoLevel()]);
+show("class expression generator:", () => [...new ExprClass()]);
+show("yield* + for-of mixed:", () => [...new Mixed()]);