diff --git a/changelog/7202.doc.rst b/changelog/7202.doc.rst
new file mode 100644
index 0000000000..2383592a4c
--- /dev/null
+++ b/changelog/7202.doc.rst
@@ -0,0 +1 @@
+:user:`bouweandela` Fixed the type hints for the :meth:`iris.cube.Cube.__init__`.
diff --git a/lib/iris/cube.py b/lib/iris/cube.py
index 6653018055..0bd3d3b018 100644
--- a/lib/iris/cube.py
+++ b/lib/iris/cube.py
@@ -1212,12 +1212,34 @@ def __init__(
         units: Unit | str | None = None,
         attributes: Mapping | None = None,
         cell_methods: Iterable[CellMethod] | None = None,
-        dim_coords_and_dims: Iterable[tuple[DimCoord, int]] | None = None,
-        aux_coords_and_dims: Iterable[tuple[AuxCoord, int | Iterable[int]]]
+        dim_coords_and_dims: Iterable[
+            tuple[
+                DimCoord,
+                int,
+            ],
+        ]
+        | None = None,
+        aux_coords_and_dims: Iterable[
+            tuple[
+                AuxCoord | DimCoord,
+                int | Iterable[int] | None,
+            ],
+        ]
         | None = None,
         aux_factories: Iterable[AuxCoordFactory] | None = None,
-        cell_measures_and_dims: Iterable[tuple[CellMeasure, int]] | None = None,
-        ancillary_variables_and_dims: Iterable[tuple[AncillaryVariable, int]]
+        cell_measures_and_dims: Iterable[
+            tuple[
+                CellMeasure,
+                Iterable[int] | int | None,
+            ],
+        ]
+        | None = None,
+        ancillary_variables_and_dims: Iterable[
+            tuple[
+                AncillaryVariable,
+                Iterable[int] | int | None,
+            ],
+        ]
         | None = None,
         shape: tuple | None = None,
     ):