diff --git a/jale/core/analyses/contrast.py b/jale/core/analyses/contrast.py
index d5cd232..abb6e6f 100644
--- a/jale/core/analyses/contrast.py
+++ b/jale/core/analyses/contrast.py
@@ -75,9 +75,14 @@ def contrast(
         )
     else:
         logger.info(f"{meta_names[0]} x {meta_names[1]} - Computing positive contrast.")
-        main_effect1 = nb.loadsave.load(
-            project_path / f"MainEffect/Volumes/{meta_names[0]}_{correction_method}.nii"
-        ).get_fdata()
+        try:
+            main_effect1 = nb.loadsave.load(
+                project_path / f"MainEffect/Volumes/{meta_names[0]}_{correction_method}.nii"
+            ).get_fdata()
+        except FileNotFoundError:
+            main_effect1 = nb.loadsave.load(
+                project_path / f"MainEffect/Volumes/{meta_names[0]}_{correction_method}_empty.nii"
+            ).get_fdata()
         significance_mask1 = main_effect1 > 0
         if significance_mask1.sum() > 0:
             stacked_masked_ma = np.vstack(
@@ -102,9 +107,14 @@ def contrast(
             z1, sig_idxs1 = [], []
 
         logger.info(f"{meta_names[1]} x {meta_names[0]} - Computing negative contrast.")
-        main_effect2 = nb.loadsave.load(
-            project_path / f"MainEffect/Volumes/{meta_names[1]}_{correction_method}.nii"
-        ).get_fdata()  # type: ignore
+        try:
+            main_effect2 = nb.loadsave.load(
+                project_path / f"MainEffect/Volumes/{meta_names[1]}_{correction_method}.nii"
+            ).get_fdata()  # type: ignore
+        except FileNotFoundError:
+            main_effect2 = nb.loadsave.load(
+                project_path / f"MainEffect/Volumes/{meta_names[1]}_{correction_method}_empty.nii"
+            ).get_fdata()
         significance_mask2 = main_effect2 > 0
         if significance_mask2.sum() > 0:
             stacked_masked_ma = np.vstack(