diff --git a/.chronus/changes/enable-skipped-python-tests-2026-4-8-8-47-0.md b/.chronus/changes/enable-skipped-python-tests-2026-4-8-8-47-0.md
new file mode 100644
index 00000000000..61bc1bc01c1
--- /dev/null
+++ b/.chronus/changes/enable-skipped-python-tests-2026-4-8-8-47-0.md
@@ -0,0 +1,7 @@
+---
+changeKind: internal
+packages:
+  - "@typespec/http-client-python"
+---
+
+Enable previously skipped client structure and client operation group mock API tests after TCGC 0.67.0 upgrade; remove obsolete `test_spread_record_discriminated_union` tests whose Spector scenario was removed.
diff --git a/packages/http-client-python/tests/mock_api/azure/asynctests/test_client_structure_async.py b/packages/http-client-python/tests/mock_api/azure/asynctests/test_client_structure_async.py
index fa58bd0f758..8d17c7a069d 100644
--- a/packages/http-client-python/tests/mock_api/azure/asynctests/test_client_structure_async.py
+++ b/packages/http-client-python/tests/mock_api/azure/asynctests/test_client_structure_async.py
@@ -38,7 +38,6 @@ async def test_structure_multiclient():
     await client_b.renamed_six()
 
 
-@pytest.mark.skip(reason="will reopen the cases after upgrade `@azure-tools/typespec-client-generator-core` to 0.67.0")
 @pytest.mark.asyncio
 async def test_structure_renamed_operation():
     client = RenamedOperationClient(endpoint="http://localhost:3000", client=ClientType.RENAMED_OPERATION)
@@ -46,19 +45,18 @@ async def test_structure_renamed_operation():
     await client.renamed_three()
     await client.renamed_five()
 
-    await client.renamed_two()
-    await client.renamed_four()
-    await client.renamed_six()
+    await client.group.renamed_two()
+    await client.group.renamed_four()
+    await client.group.renamed_six()
 
 
-@pytest.mark.skip(reason="will reopen the cases after upgrade `@azure-tools/typespec-client-generator-core` to 0.67.0")
 @pytest.mark.asyncio
 async def test_structure_two_operation_group():
     client = TwoOperationGroupClient(endpoint="http://localhost:3000", client=ClientType.TWO_OPERATION_GROUP)
-    await client.one()
-    await client.three()
-    await client.four()
+    await client.group1.one()
+    await client.group1.three()
+    await client.group1.four()
 
-    await client.two()
-    await client.five()
-    await client.six()
+    await client.group2.two()
+    await client.group2.five()
+    await client.group2.six()
diff --git a/packages/http-client-python/tests/mock_api/azure/asynctests/test_client_structure_clientoperationgroup_async.py b/packages/http-client-python/tests/mock_api/azure/asynctests/test_client_structure_clientoperationgroup_async.py
index 0b3ba88d302..96f1157418b 100644
--- a/packages/http-client-python/tests/mock_api/azure/asynctests/test_client_structure_clientoperationgroup_async.py
+++ b/packages/http-client-python/tests/mock_api/azure/asynctests/test_client_structure_clientoperationgroup_async.py
@@ -8,24 +8,22 @@
 from client.structure.clientoperationgroup.aio import FirstClient, SecondClient
 
 
-@pytest.mark.skip(reason="will reopen the cases after upgrade `@azure-tools/typespec-client-generator-core` to 0.67.0")
 @pytest.mark.asyncio
 async def test_first_client_operations():
     client = FirstClient(endpoint="http://localhost:3000", client=ClientType.CLIENT_OPERATION_GROUP)
 
     await client.one()
 
-    await client.two()
-    await client.three()
+    await client.group3.two()
+    await client.group3.three()
 
-    await client.four()
+    await client.group4.four()
 
 
-@pytest.mark.skip(reason="will reopen the cases after upgrade `@azure-tools/typespec-client-generator-core` to 0.67.0")
 @pytest.mark.asyncio
 async def test_second_client_operations():
     client = SecondClient(endpoint="http://localhost:3000", client=ClientType.CLIENT_OPERATION_GROUP)
 
     await client.five()
 
-    await client.six()
+    await client.group5.six()
diff --git a/packages/http-client-python/tests/mock_api/azure/test_client_structure.py b/packages/http-client-python/tests/mock_api/azure/test_client_structure.py
index e83d1ce6d6b..d28827376c0 100644
--- a/packages/http-client-python/tests/mock_api/azure/test_client_structure.py
+++ b/packages/http-client-python/tests/mock_api/azure/test_client_structure.py
@@ -3,7 +3,6 @@
 # Licensed under the MIT License. See License.txt in the project root for
 # license information.
 # --------------------------------------------------------------------------
-import pytest
 from client.structure.service.models import ClientType
 from client.structure.service import ServiceClient
 from client.structure.multiclient import ClientAClient, ClientBClient
@@ -36,25 +35,23 @@ def test_structure_multiclient():
     client_b.renamed_six()
 
 
-@pytest.mark.skip(reason="will reopen the cases after upgrade `@azure-tools/typespec-client-generator-core` to 0.67.0")
 def test_structure_renamed_operation():
     client = RenamedOperationClient(endpoint="http://localhost:3000", client=ClientType.RENAMED_OPERATION)
     client.renamed_one()
     client.renamed_three()
     client.renamed_five()
 
-    client.renamed_two()
-    client.renamed_four()
-    client.renamed_six()
+    client.group.renamed_two()
+    client.group.renamed_four()
+    client.group.renamed_six()
 
 
-@pytest.mark.skip(reason="will reopen the cases after upgrade `@azure-tools/typespec-client-generator-core` to 0.67.0")
 def test_structure_two_operation_group():
     client = TwoOperationGroupClient(endpoint="http://localhost:3000", client=ClientType.TWO_OPERATION_GROUP)
-    client.one()
-    client.three()
-    client.four()
+    client.group1.one()
+    client.group1.three()
+    client.group1.four()
 
-    client.two()
-    client.five()
-    client.six()
+    client.group2.two()
+    client.group2.five()
+    client.group2.six()
diff --git a/packages/http-client-python/tests/mock_api/azure/test_client_structure_clientoperationgroup.py b/packages/http-client-python/tests/mock_api/azure/test_client_structure_clientoperationgroup.py
index aa6d3c8a90d..3990830ebdb 100644
--- a/packages/http-client-python/tests/mock_api/azure/test_client_structure_clientoperationgroup.py
+++ b/packages/http-client-python/tests/mock_api/azure/test_client_structure_clientoperationgroup.py
@@ -3,27 +3,24 @@
 # Licensed under the MIT License. See License.txt in the project root for
 # license information.
 # --------------------------------------------------------------------------
-import pytest
 from client.structure.clientoperationgroup.models import ClientType
 from client.structure.clientoperationgroup import FirstClient, SecondClient
 
 
-@pytest.mark.skip(reason="will reopen the cases after upgrade `@azure-tools/typespec-client-generator-core` to 0.67.0")
 def test_first_client_operations():
     client = FirstClient(endpoint="http://localhost:3000", client=ClientType.CLIENT_OPERATION_GROUP)
 
     client.one()
 
-    client.two()
-    client.three()
+    client.group3.two()
+    client.group3.three()
 
-    client.four()
+    client.group4.four()
 
 
-@pytest.mark.skip(reason="will reopen the cases after upgrade `@azure-tools/typespec-client-generator-core` to 0.67.0")
 def test_second_client_operations():
     client = SecondClient(endpoint="http://localhost:3000", client=ClientType.CLIENT_OPERATION_GROUP)
 
     client.five()
 
-    client.six()
+    client.group5.six()
diff --git a/packages/http-client-python/tests/mock_api/shared/asynctests/test_typetest_property_additionalproperties_async.py b/packages/http-client-python/tests/mock_api/shared/asynctests/test_typetest_property_additionalproperties_async.py
index 3784156bfeb..3bded493a06 100644
--- a/packages/http-client-python/tests/mock_api/shared/asynctests/test_typetest_property_additionalproperties_async.py
+++ b/packages/http-client-python/tests/mock_api/shared/asynctests/test_typetest_property_additionalproperties_async.py
@@ -263,22 +263,6 @@ async def test_spread_model_array(client: AdditionalPropertiesClient):
     await client.spread_model_array.put(body)
 
 
-@pytest.mark.skip(reason="https://github.com/microsoft/typespec/pull/6425")
-@pytest.mark.asyncio
-async def test_spread_record_discriminated_union(client: AdditionalPropertiesClient):
-    body = {
-        "name": "abc",
-        "prop1": {"fooProp": "abc", "kind": "kind0"},
-        "prop2": {
-            "end": "2021-01-02T00:00:00Z",
-            "kind": "kind1",
-            "start": "2021-01-01T00:00:00Z",
-        },
-    }
-    assert await client.spread_record_discriminated_union.get() == body
-    await client.spread_record_discriminated_union.put(body)
-
-
 @pytest.mark.asyncio
 async def test_spread_record_non_discriminated_union(
     client: AdditionalPropertiesClient,
diff --git a/packages/http-client-python/tests/mock_api/shared/test_typetest_property_additionalproperties.py b/packages/http-client-python/tests/mock_api/shared/test_typetest_property_additionalproperties.py
index 45445d9c425..c34c281f82f 100644
--- a/packages/http-client-python/tests/mock_api/shared/test_typetest_property_additionalproperties.py
+++ b/packages/http-client-python/tests/mock_api/shared/test_typetest_property_additionalproperties.py
@@ -236,21 +236,6 @@ def test_spread_model_array(client: AdditionalPropertiesClient):
     client.spread_model_array.put(body)
 
 
-@pytest.mark.skip(reason="https://github.com/microsoft/typespec/pull/6425")
-def test_spread_record_discriminated_union(client: AdditionalPropertiesClient):
-    body = {
-        "name": "abc",
-        "prop1": {"fooProp": "abc", "kind": "kind0"},
-        "prop2": {
-            "end": "2021-01-02T00:00:00Z",
-            "kind": "kind1",
-            "start": "2021-01-01T00:00:00Z",
-        },
-    }
-    assert client.spread_record_discriminated_union.get() == body
-    client.spread_record_discriminated_union.put(body)
-
-
 def test_spread_record_non_discriminated_union(client: AdditionalPropertiesClient):
     body = {
         "name": "abc",