calculate Pc(s) in stats

[golobor]

we can calculate Pc(s) during stats computation. We'd need chromsizes (can take from pairs header, or supply an external file) and centromeres/gaps (can take from a curated database/online/external file).
via @Phlya

[agalitsyna]

What are the updates on this issue? Isn't that covered now by P(s) calculation in the current form? @golobor
Or is the idea that we also want to normalize by the chromosome size?

[Phlya]

I think the idea was indeed to include chromosome sizes into the equation. And maybe give some flexibility, like smaller bin size...

[agalitsyna]

Okay, if that's now a mature idea, maybe we can convert it into discussion? Let's wait for others and if there are no other thoughts, make it an open discussion

[agalitsyna]

pairtools scaling is out for testing: #117
Future improvements for it:

• parquet output instead of tsv
• transfer of view/region tables to bioframe's viewframe

Both of them will require additional dependencis to pairtools, which is better to avoid for the 1.0.0 release.