diff --git a/LICENSES/XSIMD_LICENSE b/LICENSES/XSIMD_LICENSE
new file mode 100644
index 0000000000000..eee7a54bc956b
--- /dev/null
+++ b/LICENSES/XSIMD_LICENSE
@@ -0,0 +1,29 @@
+Copyright (c) 2016, Johan Mabille, Sylvain Corlay, Wolf Vollprecht and Martin Renou
+Copyright (c) 2016, QuantStack
+Copyright (c) 2018, Serge Guelton
+All rights reserved.
+
+Redistribution and use in source and binary forms, with or without
+modification, are permitted provided that the following conditions are met:
+
+* Redistributions of source code must retain the above copyright notice, this
+  list of conditions and the following disclaimer.
+
+* Redistributions in binary form must reproduce the above copyright notice,
+  this list of conditions and the following disclaimer in the documentation
+  and/or other materials provided with the distribution.
+
+* Neither the name of the copyright holder nor the names of its
+  contributors may be used to endorse or promote products derived from
+  this software without specific prior written permission.
+
+THIS SOFTWARE IS PROVIDED BY THE COPYRIGHT HOLDERS AND CONTRIBUTORS "AS IS"
+AND ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE
+IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE
+DISCLAIMED. IN NO EVENT SHALL THE COPYRIGHT HOLDER OR CONTRIBUTORS BE LIABLE
+FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL
+DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR
+SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER
+CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY,
+OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE
+OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.
diff --git a/meson.build b/meson.build
index d2874e85cc3a7..33790ca88fb3f 100644
--- a/meson.build
+++ b/meson.build
@@ -37,6 +37,7 @@ add_project_arguments(
 )
 
 cc = meson.get_compiler('c')
+cxx = meson.get_compiler('cpp')
 if cc.get_id() == 'msvc'
     # Tracking issue: https://github.com/pandas-dev/pandas/issues/63701
     # Ignore some MSVC specific warnings:
@@ -44,8 +45,9 @@ if cc.get_id() == 'msvc'
     # C4267: conversion from `size_t` to smaller type.
     # C4551: occurs due to Cython generating code with (void)func.
     #        https://github.com/cython/cython/issues/3579
+    # C4146: unary minus operator applied to unsigned type. Occurs in xsimd.
     add_project_arguments(
-        ['/wd4244', '/wd4267', '/wd4551'],
+        ['/wd4244', '/wd4267', '/wd4551', '/wd4146'],
         language: ['c', 'cpp'],
     )
 endif
diff --git a/pandas/_libs/meson.build b/pandas/_libs/meson.build
index 56ff2a01b450c..674901292979d 100644
--- a/pandas/_libs/meson.build
+++ b/pandas/_libs/meson.build
@@ -53,6 +53,9 @@ _khash_primitive_helper_dep = declare_dependency(
 m_dep = cc.find_library('m', required: false)
 fast_float = subproject('fast_float')
 fast_float_dep = fast_float.get_variable('fast_float_dep')
+xsimd_dep = dependency('xsimd', version: '>=14.2')
+
+subdir('simd')
 
 subdir('tslibs')
 
diff --git a/pandas/_libs/simd/meson.build b/pandas/_libs/simd/meson.build
new file mode 100644
index 0000000000000..61925a1d90927
--- /dev/null
+++ b/pandas/_libs/simd/meson.build
@@ -0,0 +1,20 @@
+host_cpu = host_machine.cpu_family()
+
+simd_config = configuration_data()
+if host_cpu == 'aarch64'
+    simd_target = 'neon'
+    simd_config.set('PANDAS_HAVE_NEON', 1)
+elif host_cpu == 'x86_64'
+    simd_target = 'sse2'
+    simd_config.set('PANDAS_HAVE_SSE2', 1)
+else
+    simd_target = 'scalar'
+    simd_config.set('PANDAS_HAVE_SCALAR', 1)
+endif
+
+configure_file(
+    output: 'pandas_simd_config.h',
+    configuration: simd_config,
+)
+
+simd_config_inc = include_directories('.')
diff --git a/pyproject.toml b/pyproject.toml
index f5c2a5f606c1f..d03232583873c 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -38,6 +38,7 @@ license-files = [
   "LICENSES/PYUPGRADE_LICENSE", # MIT
   "LICENSES/SAS7BDAT_LICENSE", # MIT
   "LICENSES/ULTRAJSON_LICENSE", # BSD-3-Clause AND TCL
+  "LICENSES/XSIMD_LICENSE", # BSD-3-Clause
   "subprojects/fast_float-*/LICENSE-APACHE", # Apache-2.0
   "subprojects/fast_float-*/LICENSE-BOOST", # BSL
   "subprojects/fast_float-*/LICENSE-MIT", # MIT
diff --git a/subprojects/packagefiles/xsimd/meson.build b/subprojects/packagefiles/xsimd/meson.build
new file mode 100644
index 0000000000000..595fb6122ef51
--- /dev/null
+++ b/subprojects/packagefiles/xsimd/meson.build
@@ -0,0 +1,12 @@
+project(
+    'xsimd',
+    'cpp',
+    meson_version: '>=0.58.0',
+    license: 'BSD-3-Clause',
+    version: '14.2.0',
+)
+
+xsimd_inc = include_directories('include')
+
+xsimd_dep = declare_dependency(include_directories: xsimd_inc)
+meson.override_dependency('xsimd', xsimd_dep)
diff --git a/subprojects/xsimd.wrap b/subprojects/xsimd.wrap
new file mode 100644
index 0000000000000..39706456be925
--- /dev/null
+++ b/subprojects/xsimd.wrap
@@ -0,0 +1,9 @@
+[wrap-file]
+directory = xsimd-14.2.0
+source_url = https://github.com/xtensor-stack/xsimd/archive/refs/tags/14.2.0.tar.gz
+source_filename = xsimd-14.2.0.tar.gz
+source_hash = 21e841ab684b05331e81e7f782431753a029ef7b7d9d6d3ddab837e7782a40ee
+patch_directory = xsimd
+
+[provide]
+dependency_names = xsimd