With PE reads, both reads should have adapter sequence starting at the same exact position (barring rare indel errors). Scythe should check both reads at the same time to make a call, given that they're not independent. The math's beyond me, though ...
With PE reads, both reads should have adapter sequence starting at the same exact position (barring rare indel errors). Scythe should check both reads at the same time to make a call, given that they're not independent. The math's beyond me, though ...