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🧭 Overview

DeepTMInter is a deep learning framework for accurately predicting interaction sites in α-helical transmembrane proteins using sequence-derived features, enabling large-scale annotation of membrane protein interactions and analysis of drug targets.

Whether you’re working in computational drug discovery, bioinformatics, or protein science, DeepTMInter provides a ready-to-use solution for protein interactions.

📔 Documentation

Please check https://2003100127.github.io/deeptminter for its usage.

🛠️ Installation

📚 Citation

Sun, J., & Frishman, D. (2021). Improved sequence-based prediction of interaction sites in α-helical transmembrane proteins by deep learning. Computational and structural biotechnology journal, 19, 1512–1530. https://doi.org/10.1016/j.csbj.2021.03.005

In .bib form.

@article{deeptminter2021,
    title = {Improved sequence-based prediction of interaction sites in α-helical transmembrane proteins by deep learning},
    author = {Jianfeng Sun and Dmitrij Frishman},
    journal = {Computational and Structural Biotechnology Journal},
    volume = {19},
    pages = {1512-1530},
    year = {2021},
    issn = {2001-0370},
    doi = {https://doi.org/10.1016/j.csbj.2021.03.005},
    url = {https://www.sciencedirect.com/science/article/pii/S2001037021000775},
}

🏠 Developer

Jianfeng Sun

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DeepTMInter predicts interaction sites between transmembrane proteins.

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