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Ishitta-Sarkar/README.md

About

Biotechnology Graduate with a growing interest in Bioinformatics, Computational Biology, Computational Drug Discovery, Biomedical Data Science, and Machine Learning for Life Sciences.

My work focuses on applying computational methods, data-driven analysis, and artificial intelligence to biological research, disease understanding, drug discovery, and bioprocess optimization. Through research-oriented projects, I explore how biological data can be transformed into meaningful scientific insights using modern computational tools.


Research Interests

  • Bioinformatics
  • Computational Biology
  • Computational Drug Discovery
  • Molecular Docking & Virtual Screening
  • Biomedical Data Science
  • Disease Biomarker Discovery
  • Precision Medicine
  • Multi-Omics Data Analysis
  • Bioprocess Engineering
  • Artificial Intelligence for Biological Systems

Current Technical Focus

  • Python for Scientific Computing
  • Machine Learning for Biomedical Data
  • Biological Data Visualization
  • Molecular Docking Workflows
  • Biomedical Dataset Analysis
  • Drug Discovery Pipelines
  • Fermentation Process Analytics
  • Research-Oriented Data Science
  • Reproducible Computational Workflows

Featured Projects

COVID-19 Mpro Phytochemical Docking

Virtual screening workflow evaluating phytochemicals against the SARS-CoV-2 main protease using computational docking and candidate ranking strategies.

Parkinson's Voice Biomarker ML

Machine learning workflow for Parkinson's disease classification using biomedical voice measurements, exploratory analysis, visualization, and model evaluation.

Bioprocess Yield Optimization ML

Data-driven machine learning workflow for fermentation process analysis, yield prediction, and process optimization.

Computational Drug Discovery Platform

Computational pipeline for ligand screening, docking analysis, candidate prioritization, and virtual drug discovery workflows.

AI Biomarker Discovery

Machine learning-based analytical workflow for identifying potential disease biomarkers from biological datasets.

Bioinformatics Core Toolkit

Collection of bioinformatics utilities for DNA sequence analysis, FASTA parsing, mutation detection, sequence statistics, and protein translation.


Academic Background

B.Tech Biotechnology

Final Year Research Project

In Silico Molecular Docking and Virtual Screening for Identification of Potential Drug Candidates


Areas of Exploration

  • Molecular Docking & Virtual Screening
  • Computational Drug Discovery
  • Biomedical Machine Learning
  • Disease Biomarker Analysis
  • Biological Data Mining
  • Precision Medicine
  • Fermentation & Bioprocess Analytics
  • Scientific Computing for Life Sciences

Long-Term Goals

  • Computational Drug Discovery
  • Translational Bioinformatics
  • Multi-Omics Data Analysis
  • Biomedical Artificial Intelligence
  • Computational Systems Biology
  • Precision Medicine
  • Research & Development
  • Academic and Industrial Bioinformatics

Research Profile

ORCID: https://orcid.org/0009-0008-1028-6010


"Exploring the intersection of biology, computation, and data-driven discovery."

Pinned Loading

  1. bioinformatics-core-toolkit bioinformatics-core-toolkit Public

    Bioinformatics toolkit for DNA analysis, mutation detection, FASTA parsing, and protein translation using Python.

    Python

  2. ai-biomarker-discovery ai-biomarker-discovery Public

    A Python-based project for identifying potential disease biomarkers using gene expression data and analytical workflows.

    Python

  3. computational-drug-discovery-platform computational-drug-discovery-platform Public

    A Python-based framework for exploring computational drug discovery workflows including target analysis, ligand screening, molecular docking, and candidate ranking.

    Python

  4. covid-mpro-phytochemical-docking covid-mpro-phytochemical-docking Public

    Computational molecular docking workflow for virtual screening of plant-derived compounds against the SARS-CoV-2 main protease using AutoDock Vina and publicly available structural biology resources.

    Python

  5. parkinsons-voice-biomarker-ml parkinsons-voice-biomarker-ml Public

    Biomedical machine learning workflow for Parkinson's disease classification using voice-based biomarkers and real UCI dataset analysis.

    Jupyter Notebook

  6. bioprocess-yield-optimization-ml bioprocess-yield-optimization-ml Public

    Machine learning workflow for fermentation process analysis and bioprocess yield prediction using biotechnology and chemical engineering datasets.

    Python