Add optional minimap2 pass-2 aligner; default behavior unchanged - #2
Open
cwb14 wants to merge 18 commits into
Open
Add optional minimap2 pass-2 aligner; default behavior unchanged#2cwb14 wants to merge 18 commits into
cwb14 wants to merge 18 commits into
Conversation
This script summarizes self-alignment PAF data, producing best per query, reciprocal best hits, and clusters files. It includes functionality for parsing CIGAR strings and calculating metrics based on alignment data.
Added note about switching default task to dc-megablast.
# Conflicts: # README.md
# Conflicts: # README.md # tesorter2/blast_pass2.py # tesorter2/pipeline.py
Upstream renamed the project TEsorter2; the fork now follows. README and in-package docstrings/help text updated. The dated run memo under docs/runs/ keeps its original names and paths so the recorded commands stay reproducible, with a note pointing at the rename.
# Conflicts: # tesorter2/pipeline.py
…blast-task Co-Authored-By: Claude Fable 5 <noreply@anthropic.com>
minimap2 and the 70-70-70 rule remain available as opt-ins (--pass2-aligner minimap2, -rule 70-70-70). tesorter_compat gains --pass2-aligner so the minimap2 path stays reachable there. Co-Authored-By: Claude Fable 5 <noreply@anthropic.com>
WFA_TEsorter (+ source and scripts), eval.py, classify_final.py, and docs/runs/memo.md were the toolchain for tuning the minimap2 pass-2; nothing imports or invokes them. Git history preserves them. Co-Authored-By: Claude Fable 5 <noreply@anthropic.com>
This file contains hidden or bidirectional Unicode text that may be interpreted or compiled differently than what appears below. To review, open the file in an editor that reveals hidden Unicode characters.
Learn more about bidirectional Unicode characters
Sign up for free
to join this conversation on GitHub.
Already have an account?
Sign in to comment
Add this suggestion to a batch that can be applied as a single commit.This suggestion is invalid because no changes were made to the code.Suggestions cannot be applied while the pull request is closed.Suggestions cannot be applied while viewing a subset of changes.Only one suggestion per line can be applied in a batch.Add this suggestion to a batch that can be applied as a single commit.Applying suggestions on deleted lines is not supported.You must change the existing code in this line in order to create a valid suggestion.Outdated suggestions cannot be applied.This suggestion has been applied or marked resolved.Suggestions cannot be applied from pending reviews.Suggestions cannot be applied on multi-line comments.Suggestions cannot be applied while the pull request is queued to merge.Suggestion cannot be applied right now. Please check back later.
This allows users to input a library of known LTR-RTs to aid in annotation during pass-2. It also adds flexibility for using minimap2 for pass-2, which seems faster and similarly accurate in some circumstances. The default run is unchanged: blastn pass-2 with the 80-80-80 rule, exactly as on master. I verified default function is unchanged.