Hi there! My name is Lorenzo Sisti and I'm a Biochemist. I’m trained as a computational and structural biologist - although my academic background has a strong biomedical and biomolecular focus. My main research interests lie at the intersection of Biochemistry, Biophysics, and Bioinformatics, with a particular focus on:

• Proteins and antibodies structure, folding and interactions.
• Computational modeling and molecular dynamics (MD) simulations of proteins.

After a B.S. wet-lab thesis internship in Francesca Cutruzzolà's group, where I explored the interactions between metabolic enzymes of the folate cycle and nucleic acids, I joined Jan Dohnálek's Laboratory of Structure and Function of Biomolecules for an internship in crystallography and structural biology. I then transitioned to dry-lab for my M.S. thesis in Computational Biophysics at the IIT's Center for Life Nano- & Neuro-Science. In parallel, I collaborated with the Structural Bioinformatics Group at Sapienza University of Rome on molecular dynamics simulations of the DOPA decarboxylase enzyme. Since february 2025, I collaborate with the haematology department of Tor Vergata Hospital as data manager.