Update README.md#2
Open
lfnothias wants to merge 1 commit into
Open
Conversation
iprotsyuk
reviewed
Aug 3, 2017
| # MassFuser: a workflow for combining MS1 and MS2 data from replicate LC-MS runs | ||
|
|
||
| The idea behind MassFuser is to take advantage of the high resolution acquisition mode of modern mass spectrometers, and at the same time overcome its inherent limitation of longer instrument duty cycles. The principal use case of MassFuser is combining the data from replicate LC-MS runs, one of which is acquired in high resolution mode, giving accurate m/z values in MS1 scans, whereas the other one is processed with lower resolution mode and data independent MS/MS acquisition enabled. Thus, both LC-MS runs contain complementary information, which gets merged by MassFuser allowing for downstream analysis with any software tools accepting regular LC-MS data. | ||
| The idea behind MassFuser is to take advantage of the high resolution acquisition mode of modern mass spectrometers, and at the same time overcome its inherent limitation of longer instrument duty cycles. The principal use case of MassFuser is combining the data from replicate LC-MS runs, one of which is acquired in high resolution mode, giving accurate m/z values in MS1 scans, whereas the other one is processed with lower resolution mode and data independent MS/MS acquisition enabled. Thus, both LC-MS runs contain complementary information, which gets merged by MassFuser allowing downstream processing with any open software tools accepting mzML format. |
Collaborator
There was a problem hiding this comment.
@lfnothias, I totally understand your desire to make everyone use "open software tools" :) but there're proprietary tools for processing mzML files, which are compatible with MassFuser. I'd remove the word "open".
Collaborator
There was a problem hiding this comment.
As for the clarification, regarding the output format, I'd put it like "accepting regular LC-MS data in mzML format".
Collaborator
There was a problem hiding this comment.
@lfnothias jic you want your changes to be added to the repo, please update the README in your local branch as per our discussion, commit the changes, and I'll accept your pull request.
Author
|
Sounds good |
This file contains hidden or bidirectional Unicode text that may be interpreted or compiled differently than what appears below. To review, open the file in an editor that reveals hidden Unicode characters.
Learn more about bidirectional Unicode characters
Sign up for free
to join this conversation on GitHub.
Already have an account?
Sign in to comment
2 participants
Add this suggestion to a batch that can be applied as a single commit.This suggestion is invalid because no changes were made to the code.Suggestions cannot be applied while the pull request is closed.Suggestions cannot be applied while viewing a subset of changes.Only one suggestion per line can be applied in a batch.Add this suggestion to a batch that can be applied as a single commit.Applying suggestions on deleted lines is not supported.You must change the existing code in this line in order to create a valid suggestion.Outdated suggestions cannot be applied.This suggestion has been applied or marked resolved.Suggestions cannot be applied from pending reviews.Suggestions cannot be applied on multi-line comments.Suggestions cannot be applied while the pull request is queued to merge.Suggestion cannot be applied right now. Please check back later.
No description provided.