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Hands-on Biological Data Science in R

Repository containing materials and exercises for the Hands-on Biological Data Science course, offered at Ludwig Maximilian University of Munich (LMU).


📚 Course Objectives

  • Learn to use R and RStudio for biological data analysis
  • Understand core concepts in data wrangling, statistics, and genetics
  • Apply your knowledge through hands-on exercises and final projects
  • Build reproducible workflows and plots relevant to human genetics and life sciences

🧭 Course Structure

The course is structured into 6 learning modules, combining self-study, interactive sessions, assignments, and a final assignment presentation.

Module Content Format Workload (UE)
Module 1 Course Kick-off & Setup Introduction Session + R Installation 1
Module 2 R Basics & Data Operations Self-study + Exercise 1 5
Module 3 Statistics in R Self-study + Quiz + Exercise 2 5
Module 4 Genetics & GWAS Genetics Session + Exercise 3 4
Module 5 Final Assignment Self-study 3
Module 6 Presentations & Wrap-up Final session 2
Total Workload 20 UE

Note: 1 Unterrichtseinheit (UE) ≈ 45 minutes


📘 Detailed Module Breakdown

Module 1: Course Kick-off & Setup


Module 2: R Basics & Data Operations

  • Self-study: Core R syntax, tidyverse, data import/export, basic plotting
  • Exercise 1: Tasks on data manipulation and different data types, reading, plotting
  • 📁 Materials:
  • 💻 Exercises:
  • 🔍 Learning Outcomes:
    • Learn to manipulate and visualize data
    • Use tidyverse functions
    • Write basic functions

Module 3: Statistics in R

  • Self-study: Key statistical concepts and their implementation in R
  • Exercise 2: Statistics quiz and exercise in R
  • 📁 Materials:
  • 💻 Exercises:
  • 🔍 Learning Outcomes:
    • Understand p-values, CI, normal distributions
    • Perform t-tests and basic inference

Module 4: Genetics & GWAS

  • Introduscion session to complex genetics and GWAS
  • Exercise 3: Interpret GWAS output
  • 📁 Materials:
  • 💻 Exercises:
  • 🔍 Learning Outcomes:
    • Understand genetic traits and SNP association
    • Manipulate and visualize GWAS data

Module 5: Final Assignment


Module 6: Final Presentations

  • Final Assignment presentations
  • Wrap-up discussion & feedback
  • 📁 Materials:
  • 🔍 Learning Outcomes:
    • Present data analysis results clearly
    • Reflect on course content

License

This work is licensed under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0).

You are free to share and adapt the material for any purpose, even commercially, as long as appropriate credit is given.

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Repository containing materials for the Hands-on Biological Data Science course, offered at Ludwig Maximilian University of Munich (LMU).

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