Add lightweight FASTQ file format support#7924
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Add support for loading FASTQ files directly with load_dataset(). FASTQ is a text-based format for storing nucleotide sequences together with their quality scores, widely used for high-throughput sequencing. Key features: - Zero external dependencies using pure Python parser based on readfq.py - Streaming support via generator-based parsing for large NGS files - Compression support for gzip, bzip2, and xz formats - Large sequence support using large_string Arrow type - Dual-threshold batching (batch_size + max_batch_bytes) for Parquet safety Columns: id, description, sequence, quality Extensions: .fq, .fastq
This was referenced Dec 31, 2025
FastqConfig was missing the __post_init__ method that calls super().__post_init__(). This is required to inherit BuilderConfig's validation for: - Invalid config name characters (InvalidConfigName) - data_files type validation (ValueError) This aligns with the pattern used in ArrowConfig, MmcifFolderConfig, FastaConfig, and other packaged module configs. Also includes minor style formatting from ruff.
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Summary
This PR adds support for loading FASTQ files directly with
load_dataset().FASTQ is an extension of FASTA that includes quality scores for each base, widely used for storing output from high-throughput sequencing instruments.
Key Features
large_stringfor both sequence and quality columnsColumns
id@)descriptionsequencequalitySupported Extensions
.fq,.fastq(and compressed variants:.fq.gz,.fastq.gz,.fq.bz2,.fq.xz)Usage
Quality Score Format
Quality scores use Sanger/Illumina 1.8+ encoding (Phred+33):
\!(33) = quality 0I(73) = quality 40Testing
References
cc: @georgia-hf