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@lehner-lab

Lehner Lab

Software developed by members of the Lehner lab at the Centre for Genomic Regulation (CRG)

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  1. canya canya Public

    A hybrid neural network to predict nucleation propensity

    Python 8 3

  2. Stop_codon_readthrough Stop_codon_readthrough Public

    Source code for computational analyses and to reproduce all figures in the following publication: Genome-scale quantification and prediction of drug-induced readthrough of pathogenic premature term…

    3

  3. GPCR-MAPS GPCR-MAPS Public

    This repository contains the code to reproduce the analyses presented in the publication "The molecular basis of G-protein coupled receptor signaling" by Taylor Mighell and Ben Lehner

    Jupyter Notebook 1

  4. ABA_receptor ABA_receptor Public

    Forked from MaximilianStammnitz/ABA_receptor

    Companion scripts for DMS data processing, dose-response curve fitting and figure reproduction ("The genetic architecture of an allosteric hormone receptor", Stammnitz & Lehner, biorXiv 2025)

    R 1

  5. domainome domainome Public

    16

  6. DiMSum DiMSum Public

    An error model and pipeline for analyzing deep mutational scanning (DMS) data and diagnosing common experimental pathologies

    R 38 7

Repositories

Showing 10 of 47 repositories
  • pdzext Public

    Allosteric and Energetic Remodeling by Protein Domain Extensions

    lehner-lab/pdzext’s past year of commit activity
    R 0 MIT 0 0 0 Updated Dec 12, 2025
  • ABA_receptor Public Forked from MaximilianStammnitz/ABA_receptor

    Companion scripts for DMS data processing, dose-response curve fitting and figure reproduction ("The genetic architecture of an allosteric hormone receptor", Stammnitz & Lehner, biorXiv 2025)

    lehner-lab/ABA_receptor’s past year of commit activity
    R 1 1 0 0 Updated Nov 19, 2025
  • TF-MAPS Public

    TF-MAPS: fast high-resolution functional and allosteric mapping of DNA-binding proteins.

    lehner-lab/TF-MAPS’s past year of commit activity
    R 0 0 0 0 Updated Nov 7, 2025
  • src_allostery Public

    Source code for analyses and to reproduce all figures in the following publication: The allosteric landscape of Src (Beltran et al., 2023)

    lehner-lab/src_allostery’s past year of commit activity
    1 MIT 0 0 0 Updated Sep 20, 2025
  • DiMSum Public

    An error model and pipeline for analyzing deep mutational scanning (DMS) data and diagnosing common experimental pathologies

    lehner-lab/DiMSum’s past year of commit activity
    R 38 MIT 7 4 0 Updated Sep 16, 2025
  • PDZ_homologs Public
    lehner-lab/PDZ_homologs’s past year of commit activity
    HTML 0 MIT 0 0 0 Updated Jul 22, 2025
  • combinatorialcores Public

    Source code for analyses and figure reproduction in "Genetics, energetics, and allostery in proteins with randomized cores and surfaces", Escobedo et. al Science 2025

    lehner-lab/combinatorialcores’s past year of commit activity
    Jupyter Notebook 1 0 0 0 Updated Jul 21, 2025
  • lehner-lab/fas-indel-library’s past year of commit activity
    R 0 0 0 0 Updated Jun 20, 2025
  • GPCR-MAPS Public

    This repository contains the code to reproduce the analyses presented in the publication "The molecular basis of G-protein coupled receptor signaling" by Taylor Mighell and Ben Lehner

    lehner-lab/GPCR-MAPS’s past year of commit activity
    Jupyter Notebook 1 0 0 0 Updated Jun 2, 2025
  • canya Public

    A hybrid neural network to predict nucleation propensity

    lehner-lab/canya’s past year of commit activity
    Python 8 MIT 3 0 0 Updated May 7, 2025

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