Skip to content

Harmonized REF/ALT alleles #5

Description

@uncreativeusername

Could you please note in the documentation that the the ref/alt alleles need to be harmonized across studies? If the input VCF files are not harmonized, apparently APEX will not recognize the variant as shared across studies and therefore won't include the variant in the meta-analysis. Alternatively, a fix so APEX recognizes flipped ref/alt and alt/ref alleles as the same variant would be even better!

Activity

Sign up for free to join this conversation on GitHub. Already have an account? Sign in to comment

Metadata

Metadata

Assignees

No one assigned

    Labels

    No labels
    No labels

    Type

    No type

    Projects

    No projects

      Milestone

      No milestone

      Relationships

      None yet

      Development

      No branches or pull requests

      Issue actions