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Ultra-fast MRI for brain-age prediction in a real-world cognitive disorders clinic

This repository contains the data and scripts required to reproduce the results of the paper titled: Ultra-fast MRI for brain-age prediction in a real-world cognitive disorders clinic. IDs are obfuscated for privacy reasons.

The models used in the paper can be found at:

The model weights and training scripts for MCCQR_MLP are available in this repository. It builds upon the work of:

Hahn, Tim, et al. "An uncertainty-aware, shareable, and transparent neural network architecture for brain-age modeling." Science advances 8.1 (2022): eabg9471. DOI: 10.1126/sciadv.abg9471

Read the paper at:

Navarro-González, R., de Luis-García, R., Aja-Fernández, S., Liu, W., Alexander, D. C., Barkhof, F., Beament, M., Chughtai, H. R., Fox, N. C., Mummery, C. J., Rosa-Grilo, M., Thomas, D. L., Parker, G. J. M., & Cole, J. H. (2026). Ultra-fast MRI for brain-age prediction in a real-world cognitive disorders clinic. Frontiers in Aging Neuroscience, 18, 1731909. https://doi.org/10.3389/fnagi.2026.1731909

BibTeX
@article{navarro2026ultra,
  title     = {Ultra-fast MRI for brain-age prediction in a real-world cognitive disorders clinic},
  author    = {Navarro-Gonz{\\'a}lez, Rafael and
               de Luis-Garc{\\'i}a, Rodrigo and
               Aja-Fern{\\'a}ndez, Santiago and
               Liu, Wei and
               Alexander, Daniel C. and
               Barkhof, Frederik and
               Beament, Millie and
               Chughtai, Haroon R. and
               Fox, Nick C. and
               Mummery, Catherine J. and
               Rosa-Grilo, M. and
               Thomas, D. L. and
               Parker, G. J. M. and
               Cole, J. H.},
  journal   = {Frontiers in Aging Neuroscience},
  volume    = {18},
  pages     = {1731909},
  year      = {2026},
  publisher = {Frontiers Media SA},
  doi       = {10.3389/fnagi.2026.1731909},
  url       = {https://doi.org/10.3389/fnagi.2026.1731909}
}

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