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@ruvnet ruvnet commented Feb 11, 2026

Re-initialized claude-flow with --force to update agent configs,
helpers, settings, and skills for DNA analyzer swarm orchestration.

https://claude.ai/code/session_01QJhN7RNDnEHTPRVn9fMM2X

Re-initialized claude-flow with --force to update agent configs,
helpers, settings, and skills for DNA analyzer swarm orchestration.

https://claude.ai/code/session_01QJhN7RNDnEHTPRVn9fMM2X
Initial draft from swarm agent covering three-regime gate selection
based on El-Hayek, Khanna, and Abboud arXiv papers for dynamic
min-cut, hypergraph sparsification, and Gomory-Hu trees.

https://claude.ai/code/session_01QJhN7RNDnEHTPRVn9fMM2X
Comprehensive architecture design for the world's fastest DNA analyzer,
produced by a 15-agent hierarchical-mesh swarm. Documents include:

ADR Documents:
- ADR-018: DNA Analyzer Specification & DDD Architecture
- ADR-024: Deployment Architecture & Platform Strategy
- ADR-028: Graph Genome Min-Cut, Neural Intelligence, Vector Search, Security
- ADR-029: Self-Optimizing Nervous System (SONA)

DDD Domain Models:
- Epigenomics, CRISPR Engineering, Population Genomics, Pharmacogenomics

Grounded in three 2025 arXiv papers:
- El-Hayek et al.: Deterministic fully-dynamic min-cut (n^{o(1)} updates)
- Khanna et al.: Near-optimal hypergraph sparsification sketches
- Abboud et al.: Almost-linear-time Gomory-Hu trees

https://claude.ai/code/session_01QJhN7RNDnEHTPRVn9fMM2X
…chmarks, tests

- ADR-018 specification: add information-theoretic bounds, TDA, quantum-inspired algorithms
- Fix compile errors in ruvector-sparse-inference-wasm (9 errors resolved)
- Fix compile error in ruvector-fpga-transformer (BackendSpec::as_ref)
- Add HNSW genomic benchmarks (criterion) with real DNA k-mer workloads
- Add min-cut genome graph benchmarks
- Add real integration tests for core HNSW and min-cut (no mocks)
- Add ruvector-dna-bench crate for real genomic data benchmarking

https://claude.ai/code/session_01QJhN7RNDnEHTPRVn9fMM2X
ADR SOTA Enhancements (8 ADRs optimized):
- ADR-018 DDD: event sourcing, CQRS, saga patterns, hexagonal architecture
- ADR-028 Graph Genome: spectral sparsification, persistent homology, graph neural diffusion, expander decomposition
- ADR-028 Neural: state space models (Mamba/S4), ring attention, KAN, mixture-of-depths, speculative decoding
- ADR-028 Vector Search: DiskANN, RaBitQ, Matryoshka embeddings, ACORN filtered search, learned indexes
- ADR-028 Security: post-quantum crypto (Kyber/Dilithium), TFHE, SPDZ MPC, Renyi DP, Plonk/Halo2
- ADR-029 SONA: progressive nets, lottery tickets, hypernetworks, PackNet, MAML meta-learning, NAS
- ADR-024 Deployment: WebGPU, WebNN, confidential computing, unikernels, edge TPU, RISC-V RVV
- DDD-003 Epigenomics: single-cell multi-omics, TADs, methylation clocks, 4D nucleome

Code Quality (compile fixes + optimization):
- Fix warnings across ruvector-mincut, ruvllm, sona crates
- Optimize workspace Cargo.toml profiles (release, bench, release-with-debug)
- Reduce unused imports, dead code, type mismatches

Real DNA Benchmarks & Tests (no mocks):
- Benchmark suite: HNSW genomic, min-cut graph, attention, delta propagation, quantization
- Integration tests: core HNSW, min-cut, delta, SONA adaptation, Flash Attention
- Real DNA analysis pipeline example with NCBI public sequences (PhiX174, SARS-CoV-2, E.coli, human mito)
- Download script for public benchmark data from NCBI

Deliverables:
- Comprehensive README with comparison tables, QuickStart, collapsible guides
- Security audit report
- Performance optimization report

https://claude.ai/code/session_01QJhN7RNDnEHTPRVn9fMM2X
Add complete DNA analysis pipeline with 2-bit packed sequence encoding,
k-mer extraction, FASTA/FASTQ parsing, k-mer frequency embeddings,
genomic vector search, variant calling with coherence gating, and
staged pipeline orchestration. Fix ruvector-gnn-wasm native compilation
by gating WASM-only bindings behind cfg(target_arch = "wasm32").

Modules:
- sequence: 2-bit packed DNA (4x memory reduction), reverse complement
- kmer: O(1) sliding window k-mer iterator, canonical forms
- fasta: FASTA/FASTQ parser with N-base filtering
- embedding: k-mer frequency + random projection to 384-dim vectors
- search: brute-force cosine similarity index with taxonomy filtering
- variant: SNP detection with isolation-based coherence gating
- pipeline: staged parse -> QC -> embed -> search -> call pipeline

https://claude.ai/code/session_01QJhN7RNDnEHTPRVn9fMM2X
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