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guideRNAcounting

This is a sample technical coding test for entry-level bioinformatics Engineer posted on the Medium.

Problem Statement

The goal of this question is to assess the candidate’s familiarity with sequence algorithms and Python programming skills. Accordingly, there are several levels to the solution to this problem.

Solution

Reading in a fastq file and extract the sequences

Computing the spacer counts

spacer count
0 AAGTGAGCTCTTACGGGAAT 29
1 GAATGTAGTTTTAGCCCTCC 16
2 GGGATTCTATTTAGCCCGCC 17
3 TCTGATGATACCCATGCCAC 25
4 AGATTCACAGAGGCAACCTG 28

Arranging the results into specific formats (csv, text, excel, sql)

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Sample technical skills test for entry-level Bioinformatics Engineer

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