Open hotspot-guided de novo protein binder design pipeline integrating OpenMM, BindCraft, ProteinMPNN, and AlphaFold2.
computational-biology structural-bioinformatics immuno-oncology protein-protein-interactions alphafold2 contact-maps de-novo-protein-design bindcraft proteinmpnn protein-binder-design hotspot-mapping oncogenic-interfaces
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Feb 26, 2026 - Jupyter Notebook