This project applies Graph Neural Networks (GNNs) to identify rare cell populations in high-dimensional single-cell RNA sequencing (scRNA-seq) data. It constructs a graph from gene expression profiles where nodes represent cells and edges are based on similarity using FAISS nearest neighbor search.
1.Efficient graph construction from sparse gene expression matrices
2.Unsupervised GNN training with contrastive loss
3.Embedding-based clustering for rare cell detection
1.GraphSAGE
2.FAISS
3.CUDA GPU Optimization