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#treeMarkET - Forest Tree Species Marker Extraction Tool

treeMarkET is a command-line wraper designed for extracting high quality SNPs from the forest tree species.

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Installation

Pre-requisites - the programs

Option #1 (recommended)

If you use conda you can install treeMarkET pre-requisited programs by running the following commands in your terminal:

conda config --add channels bioconda
conda create --name treeMarkET
conda activate treeMarkET
conda install -c bioconda trimmomatic samtools bcftools=1.15.1 bwa

Option #2

You can also use independatly install the following programs:

trimmomatic

bwa

samtools

bcftools (>1.11)

Pre-requisites - the reference genome

Main wraper install

Download the wraper from this repository by:

git clone https://github.com/ulaszewski/treeMarkET.git

and

cd treeMarkET
chmod +x treeMarkET

Running the pipeline

Follow the installation instructions, run the script as shown below and answer the prompt questions

./treeMarkET

Output

treeMarkET provides the user with several output files:

  • clean fastq files
  • mapped, filtered and indexed bam files
  • raw and filtered maker files in *.bcf format

Please be advised that the generated files will be heavily using the your SSD/HDD up to 10x of the initial size of the input raw reads file(s). Please consider this factor while planning your reasearch.

Co-contributors

In alphabetic order: Stephen Knobloch, Bagdevi Mishra, Marco Thines, Bartosz Ulaszewski, Stefan Wötzel

Citation

If you want to cite this pipeline as well as the reference please use this DOI: https://doi.org/10.3389/fgene.2021.691058 or directly:

Mishra, Bagdevi, et al. "A Chromosome-level genome assembly of the European Beech (Fagus sylvatica) reveals anomalies for organelle DNA integration, repeat Content and distribution of SNPs." Frontiers in genetics 12 (2021).

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