MMRM 深入理解指南 - 从矩阵基础到监管应用（协方差结构、缺失数据与 MAR、REML 与 Kenward-Roger、ICH E9(R1)、SAS/R 实现）
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Sep 18, 2026 - HTML
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ich-e9
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Clinical trial protocol → Statistical Analysis Plan (SAP) auto-generation pipeline using LLM. 46 SAP sections, targeted-context, JSON structured output, protocol table extraction.
python automation sap biostatistics docx clinical-trials claude pharmaceutical llm anthropic statistical-analysis-plan ich-e9
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Apr 2, 2026 - Python
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