sacas9

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ivanjalid1 / hsv1-crispr-escape

Conservation-constrained, escape-aware CRISPR guide design for HSV-1. Finds that the sampling resolution of the public genome corpus, not repair biology, limits how low an escape probability can be demonstrated.

bioinformatics genomics reproducible-research computational-biology crispr virology cas9 preprint herpes gene-editing guide-rna antiviral hsv-1 sacas9

Updated Sep 9, 2026
Python

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